Tag Archives: Berberine 500 mg by Integrative Therapeutics

Be Kind to Your Liver

LiverJacquie Eubanks RN BSN

As the body’s largest organ, the liver performs over 500 functions, including processing everything we eat, drink or otherwise ingest. Daily lifestyle habits can either support or harm liver health. Consuming a high fiber, balanced diet filled with colorful antioxidant-rich fruits and vegetables, drinking plenty of water, exercising regularly, limiting alcohol consumption and maintaining a normal healthy weight are all factors that contribute to proper healthy liver function. Conversely, a sedentary lifestyle, an ultraprocessed diet laden with added sugar, unhealthy fats, sodium and fried foods, high alcohol consumption and excessive weight gain all put a strain on this hardworking vital organ. The journey to liver wellness begins with mindful eating, as well as a commitment to exercising three to five days each week. Daily exercise? Even better!


A reduced calorie, low sugar, low refined carbohydrate, anti-inflammatory diet can lead to improvements in liver health, and also reduces fat stored in the liver and midsection. The liver must convert surplus calories to glycogen, which is stored in the muscles, and to fat, most of which is stored in the liver and around our midsection. While there is limited storage space for glycogen, there is no limit to the amount of fat that can be created and stored. In the U.S. about 80 million people are believed to have nonalcoholic fatty liver disease (NAFLD), a common chronic condition closely linked to obesity, metabolic syndrome, high cholesterol and diabetes. Not to be confused with chronic, largely irreversible alcoholic liver disease, NAFLD is reversible in the early stages but can lead to serious health risks, including liver failure and liver cancer. NAFLD impairs toxin removal and bile production for digestion, as well as other vital liver functions.


Physical activity is a proven therapeutic strategy to improve NAFLD. Aerobic exercise helps to burn carbohydrates, proteins and fats, leading to more efficient processing and less fat storage by the liver. Studies have found that participating in endurance or resistance training several times a week can significantly reduce the amount of fat stored in liver cells, independent of  weight loss. High intensity interval training (HIIT) has been shown to be beneficial in decreasing liver fat as well. Consistent low intensity exercise can also be effective at targeting liver and abdominal fat. Studies have shown that exercise consistency is more crucial than exercise intensity. As such, those with NAFLD have a choice of training methods that can be tailored to individual preferences based on the highest likelihood of long-term compliance.

Supplemental nutrition:

Certain supplements can support efficient liver function and may enhance the effects of dietary and lifestyle changes. A healthy diet that provides a wide range of phytonutrients and antioxidant compounds can assist with detoxification. Therapeutic use of milk thistle, known for its liver-protective effects, can be traced back to antiquity, where it was traditionally used to treat liver and gallbladder disorders. Believed to support liver health and protect liver cells from toxin exposure, milk thistle comprises a group of plant compounds collectively known as silymarin. Silymarin is commonly recommended to counteract the harmful effects of alcohol on the liver, as well as speed the regeneration of injured liver cells. Due to its antioxidant and anti-inflammatory effects, silymarin may also counteract cellular free radical damage and reduce inflammation in the bile ducts. Controlled studies have found that supplementing with DHA, an omega-3 fatty acid, may aid the reduction of both liver and belly fat. Berberine, a plant compound, has been shown to reduce blood sugar and cholesterol levels and improve insulin sensitivity, benefitting those with NAFLD.

While further studies are needed, following a healthy diet, increasing physical activity and supplementing to reduce liver fat may help reverse NAFLD in its early stages, thereby decreasing the risk of progression to more serious and life threatening liver disease.

Professional Supplement Center offers these and other high quality supplements in support of healthy liver function and overall health:

Silymarin milk...Silymarin Milk Thistle Extract by Pure Encapsulations®: One serving provides 250 mg of milk thistle standardized to contain 80% silymarin and formulated to nutritionally support liver health and function. Gluten free, Non-GMO, hypoallergenic formulation.


Professional Choice... Professional Choice Omega by Professional Supplement Center®: Professional Choice Omega Alaskan IFOS Five-Star Certified fish oil provides EPA and DHA in support of healthy glucose and insulin metabolism, and cardiovascular, joint, brain, nervous system and liver health. Free of wheat, gluten, corn, yeast, soy protein, dairy products, shellfish, peanuts, tree nuts, eggs and  artificial colors, sweeteners and preservatives. Non-GMO formulation.


Berberine 500 mgBerberine 500 mg by Integrative Therapeutics®: An active constituent of plants, berberine has been utilized in traditional medicine systems for centuries. This product is formulated to support blood sugar, lipid and insulin metabolism, as well as metabolic and cardiovascular function. Free of sugar, salt, yeast, wheat, gluten, corn, soy, dairy products and artificial colors, flavors and preservatives. Vegetarian formulation.


Ultra Liver SupportUltra Liver Support by Douglas Laboratories®: This product is formulated with a synergistic blend of ingredients believed to support liver function and structure. Ingredients include extracts of milk thistle, dandelion, broccoli, schisandra, barberry and bilberry. Gluten free, Non-GMO formulation.

The Effects of Physical Exercise on Fatty Liver Disease. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954622/
Fatty Liver: What It Is, and How to Get Rid of It. https://www.healthline.com/nutrition/fatty-liver
Milk Thistle. https://www.uofmhealth.org/health-library/hn-2130007

The Impressive Health Benefits of Berberine

BerberineJacquie Eubanks RN BSN

For those who have never heard of berberine, prepare to be impressed by the therapeutic properties of this natural alkaloid compound. Revered for centuries in Ayurvedic and Traditional Chinese Medicine, berberine alkaloid extracts are well known for their significant and broad pharmacological activities, including immune enhancing, atheroprotective, antimicrobial, antibacterial, antiparasitic, antioxidant, anti-obesity and anti-inflammatory properties. Traditionally utilized for the natural treatment of intestinal infections, digestive diseases and diabetes, berberine alkaloid extracts are found in the roots, rhizomes and stem bark of plants that include Oregon grape, goldenseal, goldthread, tree turmeric and phellodendron.

Even more impressive, clinical studies have shown that berberine has glucose and cholesterol lowering properties as well. Numerous studies have shown that berberine improved endothelial dysfunction, increased glucose utilization, decreased glucose absorption in intestinal cells, significantly decreased triglycerides, increased HDL cholesterol and reduced LDL and total cholesterol, an effect similar to statin medications. In diabetic patients, berberine was shown to reduce glycemia and plasma cholesterol. In those with metabolic syndrome, berberine improved lipid and glucose profiles, and decreased body mass index and waist circumference.

Twenty-seven randomized controlled clinical trials concluded that berberine has therapeutic effects on type 2 diabetes, hyperlipidemia and hypertension with no serious side effects. In the treatment of hypertension, hypoglycemia, and high cholesterol, the study found that berberine along with lifestyle intervention tended to lower blood pressure, blood lipids and blood sugar more than a placebo or lifestyle intervention alone. Although additional randomized controlled studies are warranted, these findings suggest that berberine might be considered a potential therapeutic approach as a first line treatment for hypercholesterolemia, diabetes, hypertension, hyperlipidemia, and hypertension over an extended time period.

Along with resveratrol, berberine is one of the few known compounds to activate adenosine monophosphate-activated protein kinase (AMPK). Also known as the “metabolic master switch,” AMPK resides in the body’s cells where it plays an important role in regulating metabolism, inducing a series of events that are involved in maintaining energy homeostasis. AMPK regulates biological activities that normalize lipid, glucose and energy imbalances. When AMPK regulated pathways are dysfunctional, it can trigger symptoms of hyperglycemia, diabetes, lipid abnormalities and energy imbalances. Well-functioning AMPK helps to shift energy towards cellular repair and maintenance and helps the body return to homeostasis.

To take full advantage of Berberine’s blood glucose and lipid regulation, berberine should be taken with a meal or shortly thereafter. To keep blood levels stable, Berberine can be taken up to three times daily for a maximum intake of 1500 mg per day. Therapeutic properties support:

  • The uptake of glucose into the cells
  • Improved insulin sensitivity
  • Reduced glucose production in the liver
  • Regulation of energy balance to help control obesity and stimulate weight loss
  • Improved insulin and leptin function
  • Reduced LDL cholesterol and triglyceride levels
  • Improved HDL cholesterol levels
  • Improved metabolic function

As a promising health-promoting substance, berberine has powerful effects on various health aspects. If you are pregnant, taking medication or have a health condition, please consult a healthcare practitioner before starting any supplement regimen.

Professional Supplement Center carries these and other fine quality products to promote good health and function:

Berberine 500 mgBerberine 500 mg by Integrative Therapeutics: One capsule provides 500 mg of Berberine HCL in support of metabolic function, and healthy blood sugar and insulin metabolism. Sugar, salt, yeast, wheat, gluten, corn, soy, dairy, artificial ingredient, preservative free, vegetarian formulation.

Berberine HCLBerberine HCL by Bioclinic Naturals: One capsule provides 500 mg of Berberine HCL in support of healthy glucose metabolism, healthy blood lipids and cardiovascular health. Dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nut, artificial ingredient free, Non-GMO, vegan formulation.

Berberine Balance ...Berberine Balance by Douglas Laboratories®: This blended formula includes berberine, alpha lipoic acid and grape seed extract in support of healthy blood sugar and cardiovascular health. Yeast, wheat, gluten, soy protein, dairy, corn, sodium, sugar, starch, artificial ingredient free, vegan formulation.

Berberine SynergyBerberine Synergy™ by Designs for Health: This product supplies 400 mg of berberine plus 100 mg of alpha lipoic acid per capsule in support of optimal blood sugar and insulin levels and cardiovascular and liver health. Gluten free, Non-GMO vegetarian formulation.


Berberine 500 mg

Berberine 500 mg by Vital Nutrients: One capsule provides 500 mg of berberine HCL in support of healthy blood sugar and triglyceride levels and cardiovascualar health.


Berberine. https://www.ncbi.nlm.nih.gov/pubmed/10767672
Efficacy of berberine in patients with type 2 diabetes mellitus. https://www.ncbi.nlm.nih.gov/pubmed/18442638
Traditional Chinese Medicine in the Treatment of Metabolic Syndrome. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2467395/
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. https://www.ncbi.nlm.nih.gov/pubmed/25498346
Berberine, a plant alkaloid with lipid- and glucose-lowering properties: From invitro evidence to clinical studies. https://www.ncbi.nlm.nih.gov/pubmed/26520899