Tag Archives: Melatonin PR 3 mg Prolonged Release by Douglas Laboratories

The Right Amount of Sleep for Optimal Health

SleepOptimalHealthJacquie Eubanks RN BSN

In 1970, the iconic rock band, Chicago, released a single entitled, “Does Anybody Really Know What Time It Is?” Fast forward to 2018, one might ask, “Does anybody really know how much sleep is needed for long-term wellness?” Time marches on and science is still debating the proper amount of sleep for cardiovascular and overall health maintenance. We do know that science has linked poor sleep with chronic health challenges, including memory and concentration issues, weakened immunity, and increased risk of obesity, diabetes, high blood pressure and heart disease. Conversely, research has shown that adequate sleep can strengthen memory, curb inflammation and lower stress, as well as improve mood, spur creativity and support a healthy weight.

Individual sleep requirements are highly variable. As such, health advisors generally recommend that adults strive for an average of seven to nine hours of sleep each night. A new study suggests that sleep duration that is either too short or too long is associated with greater cardiovascular risk factors. Preliminary results from the study, recently published in an online supplement of the journal Sleep Health, suggest that seven may be the magic number when it comes to the relationship between sleep length and long-term cardiovascular health. The study showed that excess heart age appeared to be lowest among adults who reported sleeping an average of seven hours per 24-hour period. Sleeping times less than or greater than seven hours were associated with increased excess heart age, with the highest elevations noted in short sleepers.

Heart age is calculated based on risk factors for heart disease. Common reasons for advanced heart age include normal aging, family history, unhealthy diet, physical inactivity, high blood pressure, diabetes, obesity and smoking. Per the Centers for Disease Control (CDC), one in two men, and two in five women have a heart age five or more years older than their actual age. Those who slept less than seven hours had the highest risk for cardiovascular disease due to the effects of metabolic and endocrine functions, vascular damage, and circadian misalignment. Sleep deprived individuals had higher blood levels of stress hormones, as well as markers of health-damaging inflammation. Researchers also found that those who regularly slept nine or more hours each night had more calcium buildup in their heart artery walls and stiffer leg arteries than those who normally slept seven hours per night.

Research supports protected sleep time for every age group, from children to adolescents, teens and adults. Those who don’t sleep well have greater chances of developing risk factors for poor long-term health, including hypertension, high cholesterol and a higher body mass index. Cardiovascular disease is the number one cause of mortality worldwide and accounts for one of every three deaths in the U.S. Aside from age and family history, cardiovascular disease is largely preventable through addressing modifiable risk factors. Take steps to reduce cardiovascular risk factors by enjoying a whole food healthy diet, becoming physically active, not smoking and managing weight, as well as lowering blood pressure and controlling blood sugar, if needed. To lower heart age and support overall health, aim for seven hours of healthy sleep each night.

Occasional sleeplessness is normal. Nearly one third of Americans have difficulty falling and staying asleep at some point in their lives. However, when infrequent episodes of insomnia escalate to a regular unhealthy routine, poor sleep habits may be to blame. Basic sleep hygiene strategies can include keeping the bedroom cool, dark and comfortable, as well as establishing routine bed and wake up times. Avoid stimulating activities and eating a heavy meal at least three hours before bed. Begin dimming the lights at least an hour before bed to stimulate melatonin production for a good night’s rest.

To find the right amount of sleep for you, experts suggest going to bed at the same time each night for at least one week, while also setting a wake up alarm for the same time each morning. If you find you are waking before the alarm, you have likely gotten sufficient sleep and could go to bed a bit later if desired. If you sleep past the alarm, it’s a good indication that you require more sleep and need to go to bed earlier.

Professional Supplement Center offers these and other high quality formulas to support healthy sleep and overall wellness:

Melatonin Plus 5 mgMelatonin Plus 5 mg by Professional Supplement Center®: This vegetarian biphasic formulation delivers melatonin quickly, then steadily, in support of healthy sleep patterns and synchronization of daily biorhythms. Ingredients confer direct and indirect antioxidant activity. Free of wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, eggs, and artificial colors, sweeteners, and preservatives.

Melatonin PR 3 mg...Melatonin PR 3 mg Prolonged Release by Douglas Laboratories®: This formula provides 3 mg of pure grade melatonin in a prolonged-released tablet in support of healthy restful sleep. Free of yeast, wheat gluten, soy protein, dairy, corn, sodium, sugar, starch, artificial coloring, and artificial preservatives. Non-GMO vegan formulation.

Sleep TimeSleep Time by Nutritional Frontiers: To assist the promotion of restful sleep, this blended formula provides nutrients that support inhibitory neurotransmitter production as well as  promote a sense of wellbeing and reduced anxiety. Vegetarian capsules.

 

Kavinace Ultra PMKavinace Ultra PM by NeuroScience™: This top selling, highly recommended favorite provides a proprietary blend of ingredients shown to improve the onset and quality of sleep. Powerful ingredients support calming neurotransmitters and hormones important to a healthy sleep cycle to promote restorative sleep and help manage stress and anxiousness.

References:
Study links short and long sleep durations with excess heart age.  https://aasm.org/study-links-short-and-long-sleep-durations-with-excess-heart-age/
How Sleep Deprivation Affects Your Heart. https://aasm.org/study-links-short-and-long-sleep-durations-with-excess-heart-age/
Cardiovascular Disease Risk in Obstructive Sleep Apnea: an Update. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891150/
Getting too little sleep may ‘age’ the heart. https://www.reuters.com/article/us-health-heart-sleep/getting-too-little-sleep-may-age-the-heart-idUSKBN1KZ1UJ
Short and long sleep durations linked with excess heart age. https://www.sciencedaily.com/releases/2018/06/180604093121.htm
Effects of Sleep Deprivation on Your Body. https://www.reuters.com/article/us-health-heart-sleep/getting-too-little-sleep-may-age-the-heart-idUSKBN1KZ1UJ
Heart Age. https://www.cdc.gov/vitalsigns/heartage/index.html

 

Sleep More – Weigh Less

SleepWeightJacquie Eubanks RN BSN

Interestingly, one of the easiest weight maintenance rules to follow may be getting to bed at a reasonable hour. Mounting evidence shows that those struggling with weight gain may need to optimize their sleep schedules to see a more favorable number on the scale. It’s well known that controlled healthy eating and regular exercise are the top strategies for weight loss and maintenance. To avoid weight gain, prioritizing sleep may be considered an equally important approach, as inadequate sleep is associated with increased body weight and the risk for obesity. Matthew Walker, a professor of psychology and neuroscience at the University of California, Berkeley who studies the effects of sleep on weight, has found that “getting a full night’s sleep is one of the most under-appreciated factors contributing to healthy weight maintenance.”

It appears that our sleep habits directly affect diet and appetite. Researchers at the University of Chicago compared those who slept only four and one-half hours to those who slept eight hours. They found that the those who skimped on sleep did not skimp on calories the next day. In fact, quite the opposite. The short sleepers consumed an additional 400 calories and ate twice the amount of fat and protein, as compared to those who slept an optimal eight hours. Sleep deprivation results in blood alterations of certain lipids, as well as appetite regulating hormones leptin and ghrelin. Controlled studies have shown that deficient sleep leads to decreases in leptin, the satiety hormone, while ghrelin, the hunger and appetite hormone, increases. Recently, it has come to light that less than optimal sleep also results in changes to a lipid known as 2-Arachidonoylglycerol (2AG), an endocannabinoid.

The endocannabinoid system is a unique and ubiquitous cell-signaling system that is just beginning to be understood. Per the National Institutes of Health (NIH), the discovery of endocannabinoids has led to studies on their potential involvement in the physiological control of appetite and energy metabolism. The findings of three large multicenter clinical trials strongly support a pathogenic role of increased endocannabinoid activity in obesity and associated metabolic abnormalities. Studies support that endocannabinoids play a key role in memory, mood, and the brain reward systems, as well as glucose metabolism and energy balance.

Epidemiologic studies established the link between sleep deprivation and its influence on energy balance and body weight regulation processes. While a longer wake cycle results in a slight increase in energy expenditure, it can lead to disproportionate calorie consumption, decreased physical activity and weight gain. The possible involvement of reward system mechanisms may trigger increased unhealthy food intake following sleep restriction. A randomized study showed sleep restriction resulted in increased circulating concentrations of 2AG, widely expressed in the brain’s reward centers and in metabolic organs that stimulate food intake and fat lipogenesis, the metabolic formation of fat.

  • Habitual sleep loss is a major risk factor for weight gain and obesity. Generally, weight gain may occur when one gets fewer than seven hours of sleep nightly. When trying to lose or maintain weight, optimal amounts of healthy sleep may be just as crucial as diet and exercise.
  • Poor sleep causes a disruption of appetite, reward and stress hormones, resulting in increased appetite and negatively affecting the ability to make healthy food choices and control portion sizes.
  • Lack of sleep can result in daytime fatigue and deceased motivation to exercise. Sufficient healthy sleep helps to improve mental and physical performance.
  • Adequate sleep can refresh brain circuits that allow for more optimal food choices, leading to weight control rather than weight gain.
  • Just as inadequate sleep negatively affects energy levels, sufficient sleep can help provide the energy necessary for physical activity.
  • The right amount of sleep encourages proper stress and appetite hormone regulation, as well as a healthy metabolism, the amount of energy the body burns to maintain all cellular processes.
  • Adequate sleep, along with healthy diet and exercise, supports optimal health and decreased risk of developing obesity, diabetes type 2, insulin resistance and metabolic syndrome.

Professional Supplement Center carries these and other high quality products to support healthy sleep and weight maintenance:

Kavinace Ultra PMKavinace Ultra PM by NeuroScience™: This top-selling sleep product specifically targets neurotransmitter imbalances with a unique combination of neurotransmitter precursors, herbal ingredients and enzymatic cofactors that provide effective support for restful sleep. Gluten, soy, yeast and artificial ingredient free, vegetarian formulation.

 

Adipo-Leptin...Adipo-Leptin Benefits™ by DaVinci Laboratories of Vermont: This product offers evidence-based ingredients that support hormone balance relative to appetite and weight management. Gluten and soy free, Non-GMO vegetarian formulation.

 

5HTP Supreme5-HTP Supreme™ by Designs for Health: This higher dosage product supplies vitamin B6 and 5-HTP in support of appetite control, reduced cravings, insomnia, improved mood and overall neurotransmitter metabolism. Wheat, soy, dairy and preservative free, Non-GMO vegetarian formulation. This product is not recommended for those taking SSRI’s or MAO inhibitors.

 

Melatonin PR 3 mg...Melatonin PR 3 mg Prolonged Release by Douglas Laboratories: This natural hormone nutrient helps to regulate the sleep/wake cycle, supports normal immune function, and provides free radical protection. One serving provides 3 mg of pure pharmaceutical grade melatonin in a prolonged release tablet. Gluten, wheat, soy, dairy, sugar and artificial ingredient free vegan formulation.

References:
Molecular ties between lack of sleep and weight gain. https://www.nih.gov/news-events/nih-research-matters/molecular-ties-between-lack-sleep-weight-gain
The Endocannabinoid System as an Emerging Target of Pharmacotherapy. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241751/
Endocannabinoids. http://emedicine.medscape.com/article/1361971-overview#a1
Hungry for Sleep: A Role for Endocannabinoids? https://academic.oup.com/sleep/article/39/3/495/2453912/Hungry-for-Sleep-A-Role-for-Endocannabinoids
Metabolic effects of sleep disruption, links to obesity and diabetes. https://www.ncbi.nlm.nih.gov/pubmed/24937041
Impact of insufficient sleep on total daily energy expenditure, food intake and weight gain. https://www.ncbi.nlm.nih.gov/pubmed/24937041
Does Your Sleeping Schedule Affect Your Metabolism? http://healthyeating.sfgate.com/sleeping-schedule-affect-metabolism-8571.html
Sleep restriction leads to increased activation of brain regions sensitive to food stimuli. https://www.ncbi.nlm.nih.gov/pubmed/22357722