Tag Archives: Stress Suppress by Diamond Formulations

Stress: The Good, The Bad and The Ugly

StressSusan Brown Health and Wellness Editor

The Good: Stress is most often viewed negatively, but an appropriate amount of “good” stress provides the stimulation that keeps us engaged from moment to moment. Situational stress happens when we feel a sense of control over challenges and experiences we face on a daily basis. It’s a fact of life that everyday stressors, though unnerving, have become normalized and unavoidable. We live in a very stressful world, complicated by family responsibilities, work performance and social obligations, as well as serious, often unexpected life events. In immediate short-term stressful situations, the body’s acute stress response allows for the release of adrenalin, cortisol and neurotransmitters that enable the mind and body to cope with momentary challenges. This survival response results in a quickened heartbeat, rapid breathing and a rush of oxygenated blood to the heart, muscles and other organs, as well as a heightened ability to perform during stressful, yet manageable situations.

The Bad: Per the National Institutes of Health (NIH), all creatures face threats to homeostasis, which must be met with adaptative responses. Under proper functioning, once the threat or perceived fear has passed, bodily systems should return to normal balance. When stress is chronic, the central nervous system stays in a heightened alert mode, resulting in prolonged exposure to cortisol and other stress hormones. Long-term activation of the body’s stress response can cause a variety of symptoms that take a toll on overall wellbeing and put physical health at risk. This can include digestive issues, anxiety, depression, weight gain, memory and concentration issues, as well as high blood pressure, stroke and heart disease. Some of us have become so accustomed to chronic stress, that it begins to feel “normal,” and we don’t realize the huge impact stress has on our physical and mental health.

The Ugly: Although stress evolved as an adaptive response, prolonged stress can lead to tissue damage, disease and a shortened lifespan. Consequences of stress have been identified as increased harmful behaviors, such as smoking, substance abuse, and eating disorders. Chronically elevated blood pressure forces the heart to work harder and can lead to damaged arteries and plaque formation. Elevated levels of stress hormones are associated with suppressed immunity, slower wound healing, increased susceptibility to viral infections and compromised antibody response to vaccinations, including influenza, pneumonia and other infectious illnesses. Prolonged stress is also associated with heightened inflammation, as well as exacerbation of autoimmune diseases, atherosclerosis and cardiovascular disease. Perhaps even more alarming, attachment of surplus cortisol to certain memory-enhancing receptors in the brain negatively affects memory and the ability to remember.

There is no simple fix to resolve all stress inducing situations, nor any uniform proper amount of stress, as each person has an individual stress threshold, or the actual degree of stress needed to cause benefit or harm. What matters most is how one responds emotionally and physiologically to stressors. A broad based approach to stress reduction includes strategies to increase coping skills, as well as reduce pressures. Finding ways to eliminate or diminish stressors that we can control, as well as cope with stressors that are out of our control, can result in improved mental health and physical wellbeing. This can include strategies like getting proper amounts of sleep, engaging with friends or family members, being physically active, spending time in nature and taking 10 minutes of “me time” daily, to quietly sit and focus on the breath to trigger the body’s natural relaxation response.

Stressed? We can help!

Stress SuppressStress Suppress by Diamond Formulations: Our customers overwhelmingly support Stress Suppress to address symptoms of daily stress and frustration. This unique nutraceutical is formulated with specific ingredients known to support healthy levels of calming neurotransmitters that enhance the body’s ability to cope with stress, elevate mood and support relaxation without inducing drowsiness. Stress Suppress aids the body in returning to homeostasis by encouraging balanced stress and inflammatory responses, providing nutrients to improve symptoms of stress and supporting a general sense of wellbeing. Free of wheat, yeast, soy, gluten, animal and dairy products, fish, shellfish, peanuts, tree nuts, eggs and artificial colors, sweeteners and preservatives. Non-GMO kosher formulation.

References:
Lower Stress: How does stress affect the body?  https://www.heart.org/en/healthy-living/healthy-lifestyle/stress-management/lower-stress-how-does-stress-affect-the-body
STRESS AND HEALTH: Psychological, Behavioral, and Biological Determinants. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568977/
Stress Effects. https://www.stress.org/stress-effects
The Perfect Amount of Stress. https://www.psychologytoday.com/us/articles/201203/the-perfect-amount-stress

 

To Maintain Health, Protect the Gut Barrier

Protect your GutJacquie Eubanks RN BSN

It’s hard to believe that the intestinal epithelium, the largest and most important barrier between our internal and external environments, consists of a single layer of cells connected by cell-to-cell junctions that seal the intercellular space. This highly regulated and selectively permeable barrier permits the absorption of essential nutrients, electrolytes and water, and effectively defends against toxins, foreign antigens and microorganisms. As well, it maintains tissue integrity, and receives and transmits signals that affect cell behavior. Constantly challenged by the gut microbiome, the gut barrier is crucial to maintaining tissue homeostasis. For a variety of reasons, this physical barrier can become compromised. Intestinal permeability, wherein the naturally tight cellular junctions don’t function properly, allows substances not normally released to cross over into the blood stream.

Like other health syndromes, the debate continues as to whether this gastrointestinal disorder, sometimes referred to as ‘leaky gut’, is responsible for poor health. Increasingly, the association between disrupted barrier function and the development of autoimmune and inflammatory diseases has been recognized by the alternative and natural health community. The medical community at large insists there is not enough research to support the theory that leaky gut wreaks havoc within the body, which may result in a range of symptoms from fatigue, joint pain, skin problems, sleep disorders, irritability, food sensitivities and inflammatory bowel disease (IBD). Yet, other practitioners who diagnose leaky gut syndrome claim that a lack of adequate studies does not mean it does not exist.

Per the National Institutes of Health (NIH), intestinal permeability is regulated by multiple factors including exogenous factors, such as pathogens, epithelial apoptosis (programmed cell death), immune cytokines and immune cells. Immune-induced intestinal barrier dysfunction is thought to be critical in the predisposition and exacerbation of many autoimmune and inflammatory conditions including IBD, food allergy, celiac disease and diabetes. As well, chronic alcohol consumption has been shown to be associated with increased intestinal permeability, as well as inhibition of vitamin and nutrient transport and a reduction in sodium and water absorption. While not fully understood, evidence suggests the mechanism underlying alcohol-induced barrier dysfunction is related to the influx of inflammatory cells, as well as the release of various mediators, including cytokines, reactive oxygen species, leukotrienes and histamine.

Psychological and physical stress can induce a number of changes in normal gastrointestinal function that affect gut motility, permeability, mucous secretion and absorption, resulting in stress induced changes in intestinal barrier function. Long-term chronic stress is associated with an increased risk or worsening of ulcerative colitis and the exacerbation of irritable bowel syndrome (IBS), as well as functional gastrointestinal disorders. Increased permeability induced by stress is believed to play an important role in disease progression and relapse.

Non-steroidal anti-inflammatory drugs (NSAIDs) are associated with a high incidence of gastrointestinal side effects. Substantial evidence indicates that chronic use can alter intestinal barrier function, causing significant damage including ulcers, perforation, hemorrhage and exacerbation of IBD. It has become evident that acute and chronic ingestion of NSAIDs by healthy persons promotes altered intestinal barrier dysfunction.

In summation, dysregulation of the intestinal barrier has been associated with chronic immune and inflammatory diseases. High blood sugar, common in those with diabetes, obesity and other metabolic syndromes, disrupts the intestinal barrier leading to intestinal inflammation and systemic infection complications. Food allergies, pathogens, toxins, and bacteria, such as E. coli that causes food poisoning, can all alter intestinal barrier function. Whether the role of intestinal epithelial barrier function remains a factor in the predisposition for disease development, or disease results in barrier dysfunction, remains elusive. However, clinical and experimental evidence supports the role of intestinal epithelial barrier dysfunction in disease pathogenesis.

It’s clear that a vital indicator of gut health is the degree of intestinal permeability. Intestinal health is paramount for achieving and maintaining overall health and wellness, as nearly 80 percent of the immune system is housed in the gut. Immune health impacts inflammatory markers, a root indicator of chronic disease. The intestinal wall villi could be considered ground zero for inflammation and oxidative stress. Maintaining the epithelial barrier is crucial for decreasing permeability and reducing risks of associated health conditions.

Well studied L-glutamine is a unique amino acid that provides an energy source for immune cells, as well as nutrition for villi health. Clinical studies have found that L-glutamine may reduce intestinal mucosal permeability, contribute to intestinal barrier maintenance and modulate immune cells, enhancing intestinal immune function. L-glutamine is thought to improve mucosal repair and address restoration of barrier function, helping to maintain the integrity of the gut and addressing a foundational cause of many health conditions.

Professional Supplement Center offers these and other high quality products in support of a  healthy intestinal barrier:

L-Glutamine PowderL-Glutamine Powder by Designs for Health®: This powdered supplement provides 3 g of L-glutamine per serving in support of the immune and digestive tract health. L-glutamine supports the healthy function  of intestinal mucosal cells for normal healing and repair. Gluten free, Non-GMO formulation.

Comprehensive Gut...Comprehensive Gut Health by Pioneer®: This professional product is formulated to provide nutritive support for gastrointestinal health. Specific ingredients support and soothe the intestinal lining and mucous membranes to protect the gut barrier. Verified gluten free. No artificial colors, flavors or preservatives.

L-Glutamine 1,000 mgL-Glutamine 1,000 mg by Pure Encapsulations®: This hypoallergenic formulation provides 1,000 mg of free-form G-glutamine per serving in support of the mucosal lining and a healthy functioning gastrointestinal tract. Gluten free, Non-GMO vegan formulation.

Restore Gut Health...Restore Gut Health Mineral Supplement by Restore®: This premier liquid formulation is designed for complete wellbeing of the immune system and intestinal tract. Specific ingredients help to balance gut health by combatting environmental exposures and creating a healthy microbiome for good bacteria to grow and flourish. Naturally gluten free, BPA free, non-toxic formulation.

Leaky Gut WellnessLeaky Gut Wellness by Bio Nutrition: Leaky Gut Wellness is formulated to provide bowel, gastrointestinal and digestive stress support. Specific ingredients support the maintenance of a healthy mucosal barrier and aid nutrient absorption for overall wellness. Free of gluten, yeast, corn, sugar, starch, salt, milk, preservatives and artificial ingredients.

Stress SuppressStress Suppress by Diamond Formulations: Stress Suppress provides specific ingredients known to support healthy levels of calming neurotransmitters that enhance the body’s ability to cope with stress, elevate mood and support relaxation. Stress Suppress aids the body in returning to homeostasis by encouraging balanced stress and inflammatory responses, providing nutrients to improve symptoms of stress and supporting a general sense of wellbeing. Free of wheat, yeast, soy, gluten, animal or dairy products, fish, shellfish, peanuts, tree nuts, eggs, and artificial colors, artificial sweeteners and artificial preservatives. Non-GMO kosher formulation.

References:
Intestinal Barrier Function: Molecular Regulation and Disease Pathogenesis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266989/
Apoptosis in the intestinal epithelium: its relevance in normal and pathophysiological conditions. https://www.ncbi.nlm.nih.gov/pubmed/10735533
Intestinal barriers protect against disease. http://science.sciencemag.org/content/359/6380/1097