Tag Archives: Ubiquinol-QH 100 mg by Pure Encapsulations

Brain Nutrients – Food for Thought

FoodForThoughtJacquie Eubanks RN BSN

While we primarily conceive of nutrition in terms of energy production and support for building and repair processes, throughout history, many cultures have traditionally used plant foods and spices as a means for prevention and protection against disease. In modern times, the ability of dietary factors to influence brain health are only now beginning to be recognized. Over the last decade, research has provided evidence that dietary components may influence mechanisms and molecular systems that maintain mental function, more specifically synaptic plasticity. Synapses or junctions, where virtually all important brain activity emerges, effectively control neuronal communication. Plasticity is the ability of the brain to adapt to new information; synaptic plasticity is the brain’s ability to strengthen or weaken the synaptic function as a result of learning. For example, repeating song lyrics strengthens the related connections in the brain that make it possible to easily recall the words.

A sharp mind and memory formation depend on the vitality of the brain’s network of interconnecting neurons. Research has established that synaptic activity, including synapse-specific modifications of synaptic strength, plays a vital role in learning and memory. The ability to learn and remember, as well as other mental and emotional processes, can be influenced by  factors such as stress, lack of stimulation or neurotoxins that may cause synapse dysfunction. A balanced diet, adequate amounts of physical activity, proper sleep, and healthy environmental interaction appear to have the potential to alter brain heath and mental function. Nutrients that influence cognition act on the necessary cellular processes for the maintenance of brain health. Encouraging results of clinical and preclinical studies raise the possibility that dietary interventions may be a viable strategy for enhancing cognitive abilities, protecting the brain from damage, promoting repair, and counteracting the effects of aging.

Adults of all ages looking to preserve brain heath and function throughout their lifespan, should consider following a healthy lifestyle to help protect and strengthen the synapses that keep minds active and alert. Lifestyle tips for healthy brain function include stress reduction and relaxation techniques, brain stimulation though demanding intellectual tasks, cardiovascular exercise to oxygenate the brain, adequate sleep, not smoking, taking alcohol in moderation and eating a nutritious diet that includes brain supportive nutrients. Per the National Institutes of Health (NIH), select nutrients have the capacity to affect neural pathways associated with synaptic plasticity that positively affects cognitive function. These dietary components have been identified as having effects on membrane fluidity, the regulation of neurotransmitter pathways, synaptic transmission and signal-transduction pathways.

DHA Omega-3 essential fatty acids, specifically DHA, are normal constituents of cell membranes and are essential for normal brain function. Dietary consumption of omega-3 fatty acids is one of the best-studied correlations between food and brain evolution. As the human body is not efficient at synthesizing DHA, we are largely dependent on dietary sources, such as oily fish, shellfish and algae. Dietary deficiency of omega-3 fatty acids has been associated with increased risk of mental health disorders, including dementia and depression. DHA may enhance cognitive abilities by facilitating synaptic plasticity, or through its positive effects on metabolism, glucose utilization, and mitochondrial function.

Turmeric/Curcumin – Studies suggest that curcumin has bioactive antioxidant, anti-inflammatory and neuro-protective effects. Population studies have shown that those who regularly consume curcuminoids as part of their traditional cuisine, such as in India and Asia, scored significantly better on cognitive function tests. Chronic low-grade inflammation plays a major role in many degenerative conditions. Curcumin’s strong anti-inflammatory properties may inhibit inflammation at the molecular level to help prevent or fight chronic inflammation. Curcumin may also boost levels of brain-derived neurotrophic factor (BDNF), which supports synaptic plasticity and cognitive function, as well as the survival of existing neurons and the differentiation of new neurons.

Flavonoids – Flavonoids, phytochemicals found in a variety of fruits and vegetables, have been identified as promising bioactive compounds capable of influencing certain aspects of brain function, including cerebrovascular blood flow, and synaptic plasticity and strengthening. Dietary flavonoids are believed to have the potential to protect against neurotoxin damage, suppress neuroinflammation, and promote memory, learning and cognitive function.

B vitamins – Per the NIH, B complex vitamins are absolutely essential for every aspect of brain function. These synergistic micronutrients work at a cellular level to support energy production, healthy mood and cognitive performance, as well as DNA/RNA synthesis and repair, and the synthesis of numerous neurochemicals and signaling molecules.

CoQ10/Ubiquinol – Found in virtually all cell membranes, CoQ10 (ubiquinone) is a powerful antioxidant and a vital participant in oxygen utilization and cellular energy production. By aiding energy production and protecting organ cells from oxidative stress and free radical damage, CoQ10 supports the overall health of all bodily cells, organs and tissues. Animal studies have shown that oral administration of CoQ10 can exert neuroprotective effects that may prove useful in the future treatment of neurodegenerative disease.

Professional Supplement Center carries these and other high quality supplements in support of brain and overall health:

ProDHA 1000 mg...ProDHA 1000 mg Strawberry by Nordic Naturals®: This high potency formula offers research- backed benefits for brain, eye, and nervous system health, as well as emotional wellbeing. Sourced from purified deep sea fish oil. Natural strawberry flavor. Naturally preserved with rosemary extract and d-alpha tocopherol. Gluten free, no artificial ingredients, Non-GMO verified.

Ubiquinol-QH 100 mgUbiquinol-QH 100 mg by Pure Encapsulations®: This product provides Kaneka QH™, a readily absorbable, active antioxidant form of CoQ10, in support of cellular energy production, cardiovascular health and free radical protection. Gluten free, hypoallergenic, Non-GMO formulation.

Curcumin 500 with...Curcumin 500 with Bioperine by Pure Encapsulations®: This product supplies 500 mg of turmeric standardized to contain 95% curcuminoids in support of a healthy inflammatory response, cellular health, and healthy liver, colon and musculoskeletal function. Bioperine® is added for enhanced bioavailability and absorption. Gluten free, hypoallergenic, Non-GMO vegan formulation.

FlavonALLFlavonAll by Douglas Laboratories®: This broad-spectrum flavonoid-based supplement delivers eight of the most concentrated and well-researched standardized plant extracts highly regarded for their beneficial antioxidant properties. Ingredients include Pycnogenol®, as well as grape seed, bilberry, and milk thistle extracts. Soy free, vegan formulation.

Active B-ComplexActive B-Complex by Integrative Therapeutics®: This product provides the full complement of bioavailable B vitamins in support of numerous biochemical processes and overall healthy function. Gluten, wheat, dairy, soy and artificial ingredient free, vegetarian formulation.

References:
Brain foods: the effects of nutrients on brain function. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805706/
Boost your memory by eating right. https://www.health.harvard.edu/mind-and-mood/boost-your-memory-by-eating-right
Nutrients for a Sharp Memory. http://www.todaysdietitian.com/newarchives/1217p24.shtml
4 Types of Foods to Help Boost Your Memory. https://www.eatright.org/health/wellness/healthy-aging/memory-boosting-foods
Do Memory Problems Always Mean Alzheimer’s Disease? https://www.nia.nih.gov/health/do-memory-problems-always-mean-alzheimers-disease
The synaptic plasticity and memory hypothesis: encoding, storage and persistence. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843897/
10 Proven Health Benefits of Turmeric and Curcumin. https://www.healthline.com/nutrition/top-10-evidence-based-health-benefits-of-turmeric
Flavonoids and brain health: multiple effects underpinned by common mechanisms. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775888/
Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC21173/

 

Strategies To Address Dementia Risk

DementiaJacquie Eubanks RN BSNDementia is a general term for the loss of memory and intellectual abilities. Alzheimer’s disease is the 6th leading cause of death in the U.S., and the most common form of age-related dementia, contributing to 70% of the almost 50 million cases worldwide. Alzheimer’s and other forms of dementia are expected to dramatically increase as the population ages, with some estimates predicting 150 million cases by 2050. While there is currently no cure for dementia, a large body of research suggests that modifiable risk factors may hold the most promise for prevention of the progressive decline in mental function due to generalized brain deterioration.

No strategies are guaranteed to protect long term brain health. However, researchers have reviewed a large body of evidence, and have identified nine controllable risk factors, through various stages of life, that affect the likelihood of developing dementia. The study, recently published in The Lancet, brought together 24 international experts to review existing dementia research and determine strategies for prevention and intervention. As well, they looked for ways to improve care for those already living with the disease. While the focus has been on developing medicines for prevention and treatment, non-pharmaceutical preventative approaches that strengthen brain networks early in life may help reduce dementia cases by one-third.

Alzheimer’s causes a gradual decline in memory, thinking, and reasoning skills. There’s no question that many more trials and ongoing research into developing treatments is necessary, yet the researchers considered the scientific evidence strong enough to suggest that preventing dementia and age-related cognitive decline might be possible. Of course, there are no guarantees, and prevention needs to start before there are signs of decline, preferably before middle age.

The nine modifiable risk factors that affect the likelihood of developing dementia are:

  • Hypertension management. Controlled blood pressure levels aid in preserving brain blood vessel health. This is considered most effective when initiated early on in life, but management of blood pressure is advised at every age.
  • Increased physical activity. Aerobic exercise is associated with a reduced risk of cognitive impairment and dementia. Vascular risk factors are well known to be reduced by aerobic exercise. Evidence suggests that physical activity may slow the progression of neurodegenerative processes and age-related loss of synapses in the brain.  
  • Cognitive training. Mental stimulation that challenges the brain helps to strengthen the brain’s networks. Getting a good education in early life, and continuing at least through high school, may have a direct effect on the wiring of the brain. Challenging the brain may increase “cognitive reserve” built through a lifetime of continued learning and curiosity. Research has shown that those with greater cognitive reserve are better able to fend off degenerative brain changes.
  • Lose weight if needed. Being overweight or obese at midlife independently increases the risk of dementia, Alzheimer’s, and vascular dementia in later life.
  • Prevent or control diabetes. Studies suggest that people with type 2 diabetes are at a higher risk of developing Alzheimer’s and vascular dementia. Taking steps to manage diabetes may help to avoid potential cognitive decline.
  • Avoid or address hearing loss. It remains unclear whether hearing loss is the result of changes linked to dementia or whether hearing loss itself contributes to cognitive decline. Research suggests that those who experience hearing loss may be at greater risk of cognitive problems later in life than those without auditory problems.
  • Manage depression. Depression has been proposed as both a risk factor for and an early symptom of dementia. Approximately half of those with late-onset depression have cognitive impairment.
  • Remain socially active. Studies show that social interaction is key to mental health, and that those with larger social networks are 25 percent less likely to develop dementia than those with smaller networks.
  • Quit smoking. Smoking is damaging to cardiovascular and overall health and may lead to cognitive decline. Studies show that smokers have a 40 percent increased risk of Alzheimer’s and vascular dementia. Smoking causes oxidative stress, which appears to promote the formation of the amyloid plaques and neurofibrillary tangles in the brain that are closely associated with Alzheimer’s disease.

Professional Supplement Center offers these and other high quality supplements for brain health support:

Acetyl L-Carnitine...Acetyl L-Carnitine 500 mg by Douglas Laboratories®: This naturally occurring metabolite helps to maintain cellular membrane stability and restore age-related membranal changes, supporting brain and nervous system functions. As an antioxidant, it scavenges harmful superoxide radicals. Gluten, yeast, wheat, soy, dairy, corn, sodium, sugar, starch, and artificial ingredient free.

 

Ubiquinol-QH 100 mgUbiquinol QH 100 mg by Pure Encapsulations®: This product supplies Kaneka QH™ CoQ10 in its active, readily-absorbable antioxidant form; and supports cellular energy production, antioxidant protection, cardiovascular health and physical activity. Gluten free, Non-GMO formulation.

 

Phosphatidylserine...Phosphatidylserine Soy Free by Integrative Therapeutics®: Found primarily in the cell membranes of neurons, and in high concentrations in the brain and nervous system tissues, phosphatidylserine supports cognitive function and mental clarity. Gluten, yeast, wheat, soy, dairy, corn, sodium, sugar, starch, and artificial ingredient free.

 

AntiOxidant FormulaAntiOxidant Formula by Pure Encapsulations®: This synergistic, broad spectrum antioxidant formulation is designed to promote cellular health and support the body’s natural free radical defense system. Gluten and soy free, Non-GMO.

 

Longevity NutrientsLongevity Nutrients by Pure Encapsulations®: This hypoallergenic, nutrient-rich, highly bioavailable multivitamin, multi-mineral, and trace element supplement is designed for men and women over age 60 in support of healthy aging and optimal health. Gluten free, Non-GMO vegetarian formulation.

 

Vitamin D3 5000Vitamin D3 5000 by Neurobiologix: Essential for good health in aging adults, vitamin D deficiency is associated with osteoporosis and cardiovascular disease, and may also impact the development of diabetes, hypertension, dementia and Alzheimer’s. Wheat, gluten, soy, corn protein, yeast, dairy, and artificial ingredient free.

References:
Defeating Alzheimer’s disease and other dementias. http://www.thelancet.com/commissions/dementia
One-third of dementia cases could be prevented, report says. http://www.cbsnews.com/news/one-third-of-dementia-cases-could-be-prevented-alzheimers-report/
10 Early Signs and Symptoms of Alzheimer’s. http://www.alz.org/10-signs-symptoms-alzheimers-dementia.asp
2016 Alzheimer’s Statistics. http://www.alzheimers.net/resources/alzheimers-statistics/
Can Dementia Be Prevented? Education May Bolster Brain Against Risk. http://www.npr.org/sections/health-shots/2016/02/11/466403316/can-dementia-be-prevented-education-may-bolster-brain-against-risk
What is cognitive reserve? http://www.health.harvard.edu/mind-and-mood/what-is-cognitive-reserve
Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258000/
Midlife overweight and obesity increase late-life dementia risk. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100125/
Diabetes and Alzheimer’s linked. http://www.mayoclinic.org/diseases-conditions/alzheimers-disease/in-depth/diabetes-and-alzheimers/art-20046987?pg=2
The complex relationship between depression and dementia. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039168/
Friends Make You Smart. http://www.aarp.org/health/brain-health/info-11-2008/friends-are-good-for-your-brain.html
Smoking and Dementia: What to Know. https://www.healthafter50.com/memory/article/smoking-and-dementia-what-to-know

 

CoQ10 and Ubiquinol Health Benefits

CoQ10Jacquie Eubanks RN BSN

Found in virtually all cell membranes, CoQ10 (ubiquinone) is a powerful antioxidant and a vital participant in oxygen utilization and cellular energy production. Synthesized by the body and naturally found in organ meats, cold water fish, whole grains and some vegetables, the highest concentrations of CoQ10 are found in the body’s high energy organs, including the heart, kidneys, pancreas, liver, and the adrenals. CoQ10 acts as a cofactor in the mitochondrial synthesis of adenosine triphosphate (ATP). ATP transports chemical energy within the cells for metabolism and is therefore essential for the health of virtually all tissues and organs. In its significant antioxidant role, CoQ10 helps to reduce and prevent the generation of free radicals, and modifications to proteins, lipids and DNA.

In addition to its energy production and antioxidant functions, CoQ10 helps to strengthen the immune system and boost physical performance, as tissues and cells are highly energy- dependent and require a steady supply of CoQ10 for optimal function. In the body, CoQ10 exists either in its oxidized form, ubiquinone, or in its reduced form, ubiquinol, and has very unique ability to cycle back and forth between the two forms. CoQ10 aids homeostasis by either donating or accepting an electron in the chain of reactions that lead to energy production. When oxidized ubiquinone accepts an electron from another molecule, it becomes ubiquinol. When ubiquinol donates an electron it becomes oxidized ubiquinone, continuing the cycle.

The conversion of ubiquinone to ubiquinol is a process that naturally occurs in young, healthy bodies. However, the body’s ability to convert ubiquinone to the more bioavailable antioxidant form of ubiquinol is compromised by aging, certain medications and some chronic disease states. The ability to create CoQ10 begins to decline around 30 years of age. Statin drugs that lower cholesterol are known to impair production of CoQ10 as well, often resulting in side effects such as muscle pain, fatigue and memory loss. Statin drugs may also impair conversion of vitamin K1 to vitamin K2, which is critical for heart heath and other functions.

Clear and growing clinical research has found that supplementing with the bioavailable ubiquinol form of CoQ10 may offer the following benefits:

-Cardiovascular health support. CoQ10 helps to maintain optimal heart muscle function, and supports circulatory and vessel wall health. Deficiency of CoQ10 is associated with cardiovascular issues, including arrhythmia, heart failure and high blood pressure.

-Support for natural cellular energy production. CoQ10 sparks energy production in every cell, including cells of the heart, the body’s largest energy consumer. Lack of energy that many believe is a normal part of aging may actually result from low levels of CoQ10. Adding this supplement to one’s daily routine may result in higher energy levels over time, as the amount of ubiquinol accumulates and is maintained in plasma, organs and tissues.

-Overall health support. By aiding energy production and protecting organ cells from oxidative stress and free radical damage, CoQ10 supports the overall health of all bodily cells, organs, and tissues.

 -Reduced oxidative stress. Oxygen is an essential element that nourishes cells, and creates energy via cellular respiration and metabolism; processes which result free radical formation. Although beneficial in small amounts, an abundance of free radicals, when not neutralized by antioxidants, can damage DNA, and contribute to diseases and premature aging.

-Restored levels of CoQ10 depleted by medications. It has been shown that statin use leads to a decrease not only in cholesterol but also in ubiquinone. The decrease in blood levels of CoQ10 may result in impaired antioxidant protection and therefore lead to oxidative stress. Those with a family history of heart problems, those taking statin medications, or those at increased risk for cardiovascular disease should consider speaking with a healthcare provider regarding ubiquinol supplementation.

Professional Supplement Center carries many high quality supplements in support of cellular energy production and overall health:

CoQ10 100 mgCoQ10 100 mg by Integrative Therapeutics: This highly rated CoQ10 supplement supplies support for overall wellness, energy production and cardiovascular health. Gluten, wheat, dairy and artificial ingredient free formulation.

 

Coenzyme Q10 100 mg ...Coenzyme Q10 by Douglas Laboratories®: One softgel provides 100 mg of CoQ10 as ubiquinone in support of cellular energy production and antioxidant protection. The formula includes 100 IU of vitamin E as d-alpha tocopherol for enhanced absorption. Soy free.

 

Ubiquinol-QH 100 mgUbiquinol-QH 100 mg by Pure Encapsulations®: This product supplies Kaneka QH™ CoQ10 in its active, readily-absorbable antioxidant form in support of cellular energy production, antioxidant protection, cardiovascular health and physical activity. Gluten free, Non-GMO formulation.

 

Liposomal COQ10Liposomal CoQ10 by Empirical Labs: One serving provides 200 mg of CoQ10 as ubiquinone in highly absorbable liposomal form for enhanced delivery. Non-GMO formulation.

 

References:
Coenzyme Q10: The essential nutrient.   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178961/
Coenzyme Q10. http://lpi.oregonstate.edu/mic/dietary-factors/coenzyme-Q10
Coenzyme Q10. http://www.umm.edu/health/medical/altmed/supplement/coenzyme-q10
Statins lower plasma and lymphocyte ubiquinol/ubiquinone without affecting other antioxidants and PUFA. https://www.ncbi.nlm.nih.gov/pubmed/14695926