Tag Archives: vitamin K

A, D, E, and K – The Fat Soluble Vitamins

FatSolubleVitaminsJacquie Eubanks RN BSNInfluenced by their molecular properties, the solubility of nutrients determines how well they will be absorbed by the body. Whether a vitamin is soluble (dissolvable) in water or in lipids influences where it can be utilized and whether any excess will be excreted or stored. Water-soluble B-complex vitamins and antioxidant vitamin C are quickly and easily utilized; any excess intake is eliminated so daily replenishment is required. Not surprisingly, fat-soluble vitamins A, D, E and K require some dietary fat in order to be absorbed and metabolized. Excess intake of these nutrients is stored in the liver and the body’s fatty tissues until needed. Dietary fats are also required for the conversion of carotene to vitamin A, for mineral absorption, and for numerous biological processes. Vitamins A, D and K cooperate synergistically, and also work in tandem with important essential minerals like magnesium, calcium and zinc.

Nutrient deficiencies are generally the result of dietary inadequacy, impaired absorption, increased requirement, or increased excretion. While a well-balanced diet containing a wide variety of nutrient dense whole foods can provide sufficient amounts of vitamins and minerals, nutrient deficiencies are incredibly common. Unlike vitamins A, E and K that have multiple dietary sources, very few foods naturally contain vitamin D. As food sources are limited, a deficiency can occur when dietary intake is insufficient over a period of time. Since vitamin D is synthesized through skin exposure to ultraviolet radiation from sunlight, restricting sunlight exposure can also create a deficiency of this nutrient. Additionally, low serum levels of vitamin D can result from inadequate digestive absorption, or the inability of the liver and kidneys to complete the synthesis of vitamin D from ultraviolet light.

Vitamin A

Also known as retinol, antioxidant vitamin A is critical for the maintenance of normal vision, as well as the growth and specialization of virtually all bodily cells. Vitamin A has important roles in embryonic development, normal immune functions, red blood cell production and free radical scavenging. Naturally present in foods such as organ meats, salmon, dairy products and colorful fruits and vegetables, vitamin A is actually a group of nutritional organic compounds that include retinol, retinoic acid, and provitamin A carotenoids, most notably beta-carotene. Although it is best known for the ability to support eye health, vitamin A also helps to relieve inflammation and supports bone, immune, skin and tissue health.

Vitamin D

All vitamin D, whether obtained through sunlight exposure, diet or supplementation, is biologically inert. To become biologically active it and must go through conversion, first in the liver, then in the kidneys. As optimizing vitamin D levels is important to disease prevention and long term health maintenance, one must expose large amounts of skin to the proper amount of sunlight, or supplement with vitamin D3, a highly potent, quickly converted bioactive form. Actually considered a prohormone, vitamin D has the potential to provide numerous health benefits when adequate levels are maintained. Among its many functions are the facilitation of calcium, phosphate and magnesium absorption, cell growth modulation, and inflammation reduction, as well as immune and neuromuscular support. Vitamin D may play a role in protecting against certain cancers, heart disease, diabetes, stroke, autoimmune diseases and depression. As many individuals either avoid sun exposure or block ultraviolet rays with sunscreen, supplementation with vitamin D3 may be a wise choice for those who with low serum levels of vitamin D.

Vitamin E

Required for the proper function of many organs, enzymatic activities and neurological processes, antioxidant vitamin E fights free radicals, helps reduce inflammation, and works to balance hormones naturally. Found in seeds, nuts, whole grains and some fruits and vegetables, vitamin E helps boost immunity and supports blood vessel health. Although more studies are needed, vitamin E may support cardiovascular health by helping to prevent platelet clumping and plaque buildup in blood vessels. Through its ability to fight the inflammation and oxidation linked to numerous health conditions, vitamin E may aid in the prevention of cataracts, arthritis and some cancers.

Vitamin K

Well known for its crucial role in proper blood clotting, vitamin K is also essential for building strong bones and preventing heart disease. Of the three types of vitamin K, K1, K2 and K3, natural vitamin K2 is synthesized in the digestive tract and is the form most often recommended for supplementation. Viewed as an important nutritional intervention for improved bone density, vitamin K2 aids the deposit of calcium and other important minerals into the bone matrix. Additionally, published research has indicated that optimum intake of vitamin K plays an important role in longevity. By aiding calcium placement in the bones, vitamin K helps to keep calcium deposits out of arteries and blood vessels, thereby preventing  arterial calcification, or atherosclerosis, that can lead to heart attacks and stroke. Primarily present in leafy vegetables, vitamin K can be found in fermented foods and animal products, such as meat and dairy.

It can be nutritionally challenging to get the macro- and micro-nutrients the body requires, particularly when one is elderly or dieting, or has illnesses, allergies, or dietary restrictions that require the elimination of entire food groups. The result of sub-optimal intake of nutrients is a sub-optimal state of health. RDA’s, known also as Daily Values (DV), are typically based on a 2,000 calorie per day diet. With diet alone, the average American will fail to meet RDA’s for B vitamins, vitamin D, and minerals such as iron, magnesium and zinc. Even those who consciously eat a nutritious diet each day may fall alarmingly short of their RDA’s for maintaining optimal health.

Professional Supplement Center carries these and other high quality nutritional supplements in support of overall health and longevity:

Comprehensive...Comprehensive Nutritional Panel by Spectracell Laboratories: Micronutrient testing offers an accurate, scientifically proven method of assessing nutritional deficiencies. This test measures 35 nutritional components including vitamins, minerals, antioxidants, and metabolites, as well as amino and fatty acids. Test kit, shipping labels and complimentary post-test consultation with Registered Nurse included.

 

Vitamin A 10,000 IUVitamin A 10,000 IU by Pure Encapsulations®: Largely derived from Norwegian cod liver oil, this product supplies an optimum amount of vitamin A per serving in support of healthy bodily function and maintenance. Gluten and soy free, Non-GMO formulation.

 

Vitamin D 5,000 IUVitamin D 5,000 IU by Douglas Laboratories®: One tablet supplies 5,000 IU of vitamin D3 in support of calcium absorption, bone metabolism, and optimal health. Gluten, wheat, soy, dairy, sugar, yeast and artificial ingredient free, Non-GMO vegetarian formulation.

 

Natural Vitamin E...Natural Vitamin E Complex with Mixed Tocopherols by Douglas Laboratories®: One softgel provides 400 IU of pure, natural alpha, beta, gamma and delta tocopherols in support of free radical defense. Gluten and soy free formulation.

 

K2-7 plus D3K2-7 + D3 by Vital Nutrients: This synergistic formulation supports healthy serum calcium levels, healthy bone and calcium metabolism, and vascular elasticity. Gluten, wheat, dairy, soy, egg and sugar free formulation.

 

References:
Nutrients and Solubility. http://www.chemistry.wustl.edu/~edudev/LabTutorials/Vitamins/vitamins.html
Which Vitamins are Water Soluble and Fat Soluble. https://www.medicinenet.com/water_soluble_vitamins_vs_fat_soluble_vitamins/ask.htm
Vitamin D: A Hormone for All Seasons – How much is enough? Understanding the New Pressures. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240026/
The role of vitamin e in human health and some diseases. https://www.ncbi.nlm.nih.gov/pubmed/24790736

 

 

The Best Time to Take Nutritional Supplements

timingSusanBiconBy Susan Brown
Health & Wellness Editor

Those of us who regularly take vitamins and minerals to support overall health or a specific health challenge know the importance of optimal nutrition. But many may not know the ideal time of day to take specific vitamins, whether to take them on an empty stomach or with food, or what combinations of vitamins to avoid or take together. Timing really is everything, as when you take your supplements can either boost or diminish their effectiveness. According to the Council for Responsible Nutrition’s annual survey of dietary supplements, 71% of women and 65% of men take dietary supplements.

Video Timing Is Everything

By far, the most popular supplements are multivitamins and minerals, with 97% of supplement users relying on these to complement their health. While 90% of supplement users report following label information, this little primer may help those who take multi vitamins and those who take more than one supplement to receive the maximum benefit from their formulas.

Morning:

Probiotics – Probiotics are best taken on an empty stomach, so for that reason morning may be best, although some prefer to take them at bedtime. When the stomach is empty, digestive activity is quiet and stomach acid and pH balance are relatively low, increasing the chances for the helpful microorganisms to thrive.

Iron – If you are advised to take iron supplements, take them in the morning, as iron is best absorbed on an empty stomach. Caffeine, dairy and calcium can negatively affect absorption, so it’s best to avoid these for several hours after taking iron. Vitamin C, however, can aid absorption, so by all means wash the iron supplement down with orange juice or lemon water.

Multivitamins – Taking multi’s with your first meal is ideal, as the vitamins are absorbed along with the naturally occurring nutrients contained in the food. As multivitamins contain both water and fat soluble vitamins, be sure to include some healthy fats with your meal for optimal absorption. If your multivitamin formula recommends more than one capsule per day, take them in divided doses at breakfast and lunch.

B-Complex vitamins – Taking B vitamins with breakfast helps to boost your metabolism and convert your food into energy, which can be used throughout the day. As B vitamins help to fight fatigue and create energy, it’s best to avoid taking them late in the day.

Vitamin C Vitamin C is best taken in the morning to support the immune system and boost energy levels. Vitamin C is a water soluble vitamin that lasts only a few hours in the blood stream, so if your formula recommends more than 1 tablet per day, take it in divided doses with meals to get the full benefit.

Vitamin EThis fat soluble antioxidant vitamin is best absorbed when dietary fats are present, so if your breakfast includes some healthy fats, such as yogurt or nut butters, morning is a good time. Otherwise, lunch or dinner time is fine as long as you are having some healthy fats with your meal.

Fish oil – Important to support many aspects of health, fish oil is best taken with a main meal to aid absorption. Take omega-3 supplements at breakfast along with your multivitamins or if more than one capsule is recommended, take them in divided doses at breakfast and dinner.  

Afternoon:

CoQ10 – CoQ10 is involved in energy production and can be found in every cell, especially in the heart, which has high energy requirements. CoQ10 is best taken with a meal that contains dietary fats, and avoid taking it late in the day so that it doesn’t disturb your sleep.

Iodine – Iodine is not stored in the body, so regular intake is needed. Iodine supports normal cognitive function and healthy skin, and also increases energy levels. Table salt is fortified with iodine, but if you are not a regular salt user or use unadulterated salt, kelp tablets taken with lunch may boost midday energy levels.

Vitamin D – Vitamin D is best taken with a meal that contains dietary fats. It’s possible that Vitamin D can negatively affect sleep, so lunch time is a good time to get your Vitamin D.

Vitamin K – Vitamin K is best absorbed along with dietary fats and ideally should be taken along with calcium, vitamin D and vitamin C. Avoid taking vitamin K if you are taking Coumadin or any anticoagulant prescription drug, as Vitamin K can interfere with the effects of the medication.  

Evening:

Calcium – Calcium aids nerve transmission and muscle function. To get the full benefit, take calcium in the evening along with magnesium.

Magnesium – Magnesium has a calming effect on the muscles and nervous system and may aid restful sleep. Magnesium works synergistically with calcium, so take these together either as individual supplements or in a combined formula.

In addition:

Digestive Enzymes – Digestive enzymes can be taken with any meal or within 30 minutes of your meal. Unless you have serious digestive issues, they don’t necessarily need to be taken with light meals or snacks, but can be very beneficial for optimal breakdown and absorption of nutrients when taken with main meals.

FiberFiber supplements may be taken either first thing in the morning or before bed. Be sure to take fiber with a full glass of water and get plenty of water during the day. Always check with your healthcare provider before taking any fiber supplement, as fiber may delay or reduce the absorption of certain medications. Additionally, do not take fiber supplements at the same time as medications.

Should you have any questions about the best time to take any supplements, please call or email Professional Supplement Center. If you are taking any medications, check with your healthcare provider or your pharmacist before starting any supplement regime.

References:
Taking iron supplements.
Best Time to Take Probiotics.
Best Time of Day to Take Vitamins.
Psyllium.
Vitamin K.

Vitamin K’s Role In Health Support

VitKJacquieIconBy Jacquie Eubanks
BSN, RN
 

Many of us are familiar with the mainstream vitamins A, B, C, D and E. If you have not yet heard about the benefits of vitamin K, read on, as it is fast becoming known as a key player in bone and cardiovascular health. Derived from the German word “koagulation,” vitamin K is actually a group of fat soluble vitamins that play a major role in blood clotting, protein synthesis and calcium uptake in bones. With vitamin K deficiency, bones can weaken, arteries and other soft tissues can calcify, blood clotting is critically impaired and the risk of excessive bleeding and osteoporosis is increased.

Naturally occurring vitamin K1, or phylloquinone, is photosynthesized by plants, especially green leafy vegetables, making it the most predominant dietary form. Together with the liver, vitamin K1 helps to maintain healthy blood clotting. Vitamin K2, the most biologically active form, includes a range of vitamins, known as menaquinones. Vitamin K2 is synthesized by the microbiota located in the intestinal tract and can also be found in fermented foods. Vitamin K2 is utilized by blood vessel walls, bones and other tissues.

Even as our bodies make the most of all forms of vitamin K, the body’s ability to store vitamin K is limited. As such, stores are rapidly depleted and must be replenished on a daily basis. To increase your dietary intake, fermented soy-based foods naturally high in vitamin K2 such as natto, miso and tempe, are recommended. Naturally occurring vitamin K2 is often utilized in supplement formulations. Studies suggest that the absorption rate of supplemental vitamin K is higher than the rate of dietary absorption. A note of caution, those who take blood thinning medications that influence blood clotting, should avoid supplementing with vitamin K and should discuss their dietary vitamin K intake with their healthcare professional.  

True vitamin K deficiency, which can lead to excessive bleeding, is rare. Mild deficiencies can be caused by poor diet, medications, antibiotics and diseases such as celiac, liver, gallbladder or Crohn’s. Studies show that many of us may get enough Vitamin K from our diets to maintain adequate blood clotting but not enough to protect against arterial calcification, cardiovascular disease or osteoporosis. Most importantly, taking calcium without complimentary nutrients, namely magnesium, vitamin D3 and vitamin K, can have adverse effects, including the buildup of plaque in coronary arteries.

  • Vitamin D helps bones absorb calcium. However, it’s the vitamin K that directs calcium into the bones and prevents it from being deposited in the soft tissues, organs and arteries.
  • The very complex process of clotting is dependent on at least 12 proteins, four of which require vitamin K to complete the process.
  • Research shows that a high intake of natural vitamin K2 may be cardio-protective through a reduced risk of arterial calcification.
  • Vitamin K2 is essential for the proper synthesis of the bone protein, osteocalcin, often used as a marker for bone formation processes. Higher blood levels of osteocalcin are well correlated with increased bone mineral density, as it helps to bind calcium into the bone matrix.  
  • Increasing evidence shows that vitamin K improves bone health and reduces the risk of bone fractures, especially in postmenopausal women at risk for developing osteoporosis.
  • Vitamin K is believed to be a critical nutrient for protecting cells that line blood vessels, including arteries and veins.

Now that you know about the role of vitamin K in protecting the health of your heart, blood vessels, organs and bones, here are great recommendations for supplementation:

K-Force
 K-Force by Ortho Molecular – This supplement provides support for cardiovascular and bone health with a formulation that contains 180 mcg of K2 (as MK-7) plus 5000 IU of vitamin D3 per capsule. Gluten, yeast and soy free formula.
 
 
 
Vitamin K2 Menaquinone 7 (200913)
 
Vitamin K2 Menaquinone 7 (200913) by Douglas Laboratories – Each vegetarian capsule provides 90 mcg of Vitamin K2 as menaquinone-7. Wheat, soy, gluten and dairy free formula.
 
 
 
Vitamin K2 Liquid (1mg/drop) (K170)
 
 Vitamin K2 Liquid (K-170) by Thorne Research – This convenient, concentrated liquid form of vitamin K2 (as MK-4) provides 1 mg per drop in support of bone health. Non-GMO, gluten, soy and dairy free.
 
 
K1-1000™ (Vitamin K-1)
 
Vitamin K1 -1000™ (Vitamin K-1) by Bio-Tech – This supplement provides 1000 mcg of vitamin K1 per capsule in support of normal blood clotting and bone health. Gluten and soy free.
 
 
Rebuild Plus Osteoporosis Formula
 
Rebuild Plus Osteoporosis Formula by Metabolic Maintenance – This balanced formula contains magnesium, calcium, vitamin D3, and vitamin K1, plus additional minerals in support of healthy bones. Vegetarian capsule, excipient-free.