Tag Archives: Zyflamend Whole Body by New Chapter

What is Inflammaging?

InflammagingJacquie Eubanks RN BSN

As one of the most intricate and complex biological phenomenons, aging is often termed “senescence”, which literally means to grow old. While theories abound as to why immune system efficiency decreases with age, some research suggests that just as other bodily cells become senescent, immune cells do as well. Seen as one of the hallmarks of age progression, senescent cells do not divide or support their respective tissues; instead they emit a range of potentially harmful pro-inflammatory chemicals, encouraging nearby cells to enter the same senescent state. These “death-resistant” cells degrade tissue function, increase levels of chronic inflammation and may eventually raise cancer risk.

Senescent cells normally destroy themselves through apoptosis, programmed cellular self-destruction that occurs as part of the controlled, predictable and normal routine of an organism’s growth and development. In apoptosis, proteins within the cells break down the cellular components necessary for survival and spur the production of enzymes that destroy  DNA. The shrunken cells send out distress signals that are answered by macrophages, scavenging white blood cells that clear away cellular debris, ideally leaving nothing that can cause further damage.

However when the immune system weakens with age, significant numbers of senescent cells can escape the cleanup process. As a consequence of inappropriate cell destruction and clearance, cell debris accumulates with age, setting the stage for persistent inflammation. Chronic inflammation that accompanies aging, known as “inflammaging”, is believed to be a significant risk factor for the development of age-related diseases. In other words, chronic inflammation correlates with the downregulation of the innate immune system and may also drive the aging process itself.

During the aging process, alterations in the innate immune system may also impact adaptive immune changes, which may explain the increased incidence of infections, cancers and chronic diseases in older persons. It has yet to be determined whether diseases are caused by inflammaging alone or immunosenescence alone. Yet, researchers propose that inflammaging is accompanied by immunosenescence and that they occur together. As chronic progressive inflammation is a main feature of the gradual aging process, managing and reducing inflammaging is a potential therapeutic approach for treating and preventing age-related diseases, which often originate in mid-life.

Poor diet, a sedentary lifestyle, persistent stress, environmental toxins and second hand tobacco smoke all contribute to inflammation. Those who follow the standard American diet of refined, processed and manufactured foods may exist in a constant pro-inflammatory state. A high sugar and processed food diet feeds harmful gut microbiota that play a central role in inflammaging by releasing pro-inflammatory chemicals. An anti-inflammatory diet positively influences the microbiome by emphasizing fresh foods, whole grains, seafood, beans and legumes, thereby reducing inflammation and providing steady energy, as well as omega-3 essential fatty acids, dietary fiber, vitamins, minerals and protective phytonutrients.

Professional Supplement Center offers these and other high quality products in support of immune heath and a healthy inflammatory response:

Zyflamend Whole BodyZyflamend™ Whole Body by New Chapter®: This time-honored, whole body herbal formula is intended to balance and support the body’s natural healthy inflammatory response, as well as address minor pain and stiffness. Ingredients include turmeric, ginger, holy basil, rosemary and oregano. Gluten free, Non-GMO vegetarian formulation.

Immune Support, Q.Immune Support, Q. by Quantum Nutrition Labs: This live-source botanical and phytonutrient formulation is designed to benefit the immune and cardiovascular systems. Ingredients include medicinal mushrooms, quantum state olive leaf extract and more. Artificial ingredient free, vegan formulation.

AntiOxidant FormulaAntiOxidant Formula by Pure Encapsulations®: AntiOxidant is formulated with a broad spectrum of antioxidant vitamins, minerals, botanicals and phytonutrients to help protect against cellular free radical damage throughout the body. Gluten free, Non-GMO, hypoallergenic formulation.

Vital ClearVital Clear® by Vital Nutrients: This full spectrum formula provides quality macro-, micro- and botanical nutrients to support a healthy inflammatory response, as well as promote detoxification. Free of gluten, wheat, dairy, soy, egg and sugar.

 

References:
Macrophages. https://www.sciencedirect.com/topics/medicine-and-dentistry/macrophage
What is apoptosis? https://science.howstuffworks.com/life/cellular-microscopic/apoptosis.htm
Senescent Cells and Senolytics. https://www.leafscience.org/senolytics/
An Update on Inflamm-Aging: Mechanisms, Prevention, and Treatment. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963991/
Understanding how we age: insights into inflammaging. https://longevityandhealthspan.biomedcentral.com/articles/10.1186/2046-2395-2-8

Silencing Inflammation

SilencingInflammationJacquie Eubanks RN BSN

By now, many recognize the difference between a healthy acute inflammatory response versus an unhealthy persistent one. Acute inflammation is a necessary and vital short-term immune response to an injury, pathogenic invasion, damaged tissue, or toxic chemical effects. Systemic low-grade chronic inflammation is a long-term health damaging and unnecessary inflammatory response that can continue unnoticed and unabated for years. This prolonged state of emergency keeps the immune system’s first responders on high alert, eventually triggering disease processes that can cause lasting damage to the heart, brain, blood vessels, joint, cells and other organs.

Researchers continue to study the effects of chronic inflammation to seek an understanding of triggers that in some cases cause the body to attack its own healthy tissues. More than eighty autoimmune diseases have been identified, including rheumatoid arthritis, lupus and multiple sclerosis. Genetics may play a role, as autoimmune diseases tend to run in families, and women, in particular, have a higher risk for developing certain autoimmune conditions. Depending upon the disease, flare ups may be followed by periods of time when uncomfortable symptoms may temporarily subside. The ultimate goal of treatment is to reduce symptoms, control the autoimmune process and maintain the body’s ability to fight disease, as when the immune system is overwhelmed, it will prioritize defense over repair.

Culprits that can contribute to inflammation:

Visceral fat: Deep belly fat is thought to be a major cause of inflammation, as metabolically active fat cells release numerous hormones and chemical messengers that can lead to leptin and insulin resistance. These factors also ultimately contribute to increased appetite and fat accumulation, and consequently even higher levels of inflammation.

Gluten: Foods that contain wheat, including durum, rye, barley and ancient grains, as well as beer and malt beverages, can cause an immune response in those with sensitivities, allergies or celiac disease. This includes bakery goods, pasta, cereal, soy sauce, pretzels, tortillas, salad dressings, veggie burgers and many other products and condiments. Eliminating gluten from the diet helps to calm inflammation in many people.

Dairy and casein: As numerous food allergies result from specific types of proteins, those who are  sensitive to casein proteins found in dairy, or who are lactose (milk sugar) intolerant should eliminate dairy from their diets. Casein allergies or intolerances can result in gastrointestinal problems, joint pain, fatigue and behavioral changes. Eliminating dairy/casein from the diet also means eliminating a top source of calcium. Green leafy vegetables, bone broth, and dried fruits all provide a rich source of absorbable calcium for those excluding dairy. Be sure to include foods rich in vitamins K1 and K2, which are essential for calcium utilization, such as fermented foods and greens.

Sugar: Research has confirmed the link between added sugar and higher inflammatory markers, like C-reactive protein. A diet high in refined carbohydrates and added sugars can lead to obesity, insulin resistance, increased gut permeability, oxidative stress, and chronic low-grade inflammation. Additionally, the risk of developing heart disease, cancer, diabetes, arthritis, mental decline, and other chronic diseases increases with excess sugar consumption. Natural sugars found in fruits and vegetables have not been linked to inflammation, and many, in fact, may be anti-inflammatory.

Good lifestyle habits can help reduce inflammation:

Read food labels. Look for hidden sources of added sugar in processed foods, flavored yogurts, and cereals, as well as more obscure sources of gluten, such as brewer’s yeast, oatmeal, sausages and candy.

Eat more vegetables and fruits that contain fiber, antioxidants, vitamins, and minerals to combat and reduce inflammation. Regularly consume anti-inflammatory spices, including turmeric, garlic, ginger, cinnamon and cayenne pepper, to help reduce symptoms of pain and inflammation. Used traditionally in Ayurvedic medicine, turmeric helps control inflammation, and has shown some potential against inflammation linked diseases such as diabetes, Alzheimer’s, rheumatoid arthritis and ulcerative colitis.

Regularly consume antioxidant-rich foods such as nuts, beets, cruciferous vegetables, berries, leafy greens, cherries, and artichokes. Numerous plant bioactive components have been shown to have pharmacological properties that counteract various acute and chronic diseases. Per the National Institutes of Health (NIH), the impact of oxidative stress and resulting free radical production can lead to imbalances of enzymatic processes, resulting in cell damage and health issues. Insufficient antioxidant compounds in the daily diet can lead to the development of degenerative diseases, including cancers, cardiovascular diseases, Alzheimer’s, neurogenerative diseases and inflammatory conditions.

Exercising regularly and effectively managing stress levels can also help fight inflammation. Stress can be particularly harmful when it comes to inflammation, as it can alter gene expression in immune cells, making them more likely to attack the body’s own tissues.

Maintain a healthy weight, as obesity triggers a cascade of cellular inflammation that leads to metabolic conditions including insulin resistance. Losing excess body fat helps to normalize blood sugar levels, reduces inflammation and, in some cases, results in type 2 diabetes reversal.

Be moderate in alcohol consumption, as alcohol is a known contributor to many diseases and disorders some of which are linked to inflammation. Heavy drinking can lead to a condition known as “leaky gut” that can drive widespread inflammation and lead to organ damage.

Make an all out effort to cease smoking. In addition to causing morbidity and mortality, cigarette smoke causes diverse changes in immunity that lead to increased inflammation, impaired immune response to pathogens, and suppressed anti-tumor immune cell functions.

Professional Supplement Center offers these and other high quality products to help reduce inflammation and support overall health:

Zyflamend Whole BodyZyflamend™ Whole Body by New Chapter®: This 100% botanical full spectrum formula delivers turmeric, ginger, rosemary and other plant extracts in support of the body’s natural healthy inflammatory response, as well as the relief of minor pain or soreness associated with exercise. Naturally gluten free, Non-GMO vegetarian formulation.

Boswellia-Turmeric...Boswellia-Turmeric Complex by Douglas Laboratories®: This product provides a synergistic blend of three standardized botanical extracts in support of a healthy inflammatory response and free radical protection. Includes boswellia, turmeric, and devil’s claw, which are beneficial for connective tissues, including joints, ligaments and cartilage. Free of yeast, wheat, gluten, soy, milk/dairy, corn, sugar, starch, artificial coloring, artificial preservatives. Non-GMO formulation.

Vital ClearVital Clear® by Vital Nutrients: This powdered formula provides 29 grams of non-GMO rice protein and pea protein isolate, as well as a full range of high quality naturally pure macro-and micro-nutrients. Vital Clear® supports healthy blood sugar maintenance, detoxification, and suppressed  inflammation. Free of binders, gluten (wheat, rye, barley), milk/dairy (casein, whey), soy protein, egg protein, and sugar. Natural pineapple flavor.

Homocysteine...Homocysteine Response™ by Innate® Response Formulas: Skillfully crafted with organic whole food ingredients, this formula helps maintain healthy levels of homocysteine in the body. Elevated homocysteine levels are associated with fat accumulation, as well as tissue and organ damage. Provides specific vitamins, bioactive enzymes, trace minerals and branch chain amino acids. Gluten, wheat, soy, preservative and artificial ingredient free. Assayed for purity and potency.

References:
Why You Should Pay Attention to Chronic Inflammation. http://sugarscience.ucsf.edu/hidden-in-plain-sight/
5 Ways to Reduce Inflammation. https://chopra.com/articles/5-ways-to-reduce-inflammation
11 Food Rules For The Ultimate Anti-Inflammatory Diet. https://www.mindbodygreen.com/0-22607/11-food-rules-for-the-ultimate-antiinflammatory-diet.html
Sources of Gluten. https://celiac.org/live-gluten-free/glutenfreediet/sources-of-gluten/
Casein Protein Intolerance: https://healthyeating.sfgate.com/casein-protein-intolerance-2028.html
Does Sugar Cause Inflammation in the Body? https://www.healthline.com/nutrition/sugar-and-inflammation
Cigarette Smoking and Inflammation. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261116/
12 Healthy Foods High in Antioxidants.
Hidden in Plain Sight. http://sugarscience.ucsf.edu/hidden-in-plain-sight/
Autoimmune disorders. https://medlineplus.gov/ency/article/000816.htm
Best Spices for Arthritis. https://www.arthritis.org/living-with-arthritis/arthritis-diet/best-foods-for-arthritis/best-spices-for-arthritis.php
The Role of Antioxidants and Natural Products in Inflammation. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075620/

 

Live Healthier – Longer

challenegelivinglongerJacquie Eubanks RN BSN

The good news is that the average person’s lifespan is now almost a decade longer than it was 30 years ago. The bad news is that the overall state of health has not improved along with increased life expectancy. This means that for millions of Americans chronic pain and chronic diseases, which often result in disabilities, are impeding enjoyment of those final additional years. Topped only by ischemic heart disease, low back and neck pain now ranks number two on the list of “Disability Adjusted Life Years” (DALY’s), a study conducted by the Institute for Health Metrics and Evaluation at the University of Washington that was recently published in The Lancet. In addition to back and neck pain, the Centers for Disease Control (CDC) estimates that nearly 15 million Americans live with severe joint pain.

The majority of joint pain is linked to arthritic conditions, while back and neck pain are linked to a high body mass index (BMI) and poor physical fitness. While life expectancy has increased since 1980, obesity has increased by 28% worldwide, leading one to conclude that efforts to stem the tide of obesity have been very unsuccessful thus far. Excess weight overstresses the back and joints, leading to pain and disability. According to CDC researcher, Kamil Barbour, the level of discomfort of joint pain “can limit a person’s ability to perform basic functions and seriously compromise their quality of life.” Arthritic conditions, which affect an estimated 52 million Americans, are expected to continue to increase as the population ages.

  • Almost 50% of adults who say they are disabled and unable to work cite severe joint pain as the cause of their disability.
  • Maintaining a healthy weight, or losing weight if needed, may be one of the most beneficial ways to reduce pressure on the joints. Carrying around additional weight puts unnecessary stress on the joints and bones.
  • The researchers cited low-impact physical activity, such as walking, biking or swimming, as a nonpharmacological and underused way of reducing pain.
  • Getting sufficient amounts of calcium, phosphorus and vitamin D supports bone health and strength.
  • Following a Mediterranean style anti-inflammatory diet, that includes a high volume of nutritious plant foods, provides fiber and phytonutrients such antioxidants, lycopene, anthocyanins, and resveratrol, which discourage inflammation and support overall good health.
  • While OTC pain relievers and anti-inflammatories may help make pain bearable, they are not without side effects. The risk of side effects is greater for those with preexisting medical conditions such as heart or kidney disease. The risk factors for side effects are lower in those who generally take care of themselves by maintaining a healthy weight, exercising regularly, and controlling their blood sugar and blood pressure.

The majority or up to 80% of adult men and women experience low back pain at some point during their lifetimes. Most low back pain is mechanical in nature, resulting from an accident, injury, sedentary lifestyle, and general degeneration of the spine associated with normal age-related wear and tear on joints, discs and bones. With self-care, acute or short term back pain normally lasts from a few days to a few weeks and often resolves with no residual loss of function. Chronic back pain that persists for 12 weeks or longer can be related to a number of medical conditions including but not limited to herniated or ruptured discs, sciatica, spinal stenosis and osteoporosis.

  • Back pain becomes more common with advancing age, as bone strength, muscle elasticity, and overall flexibility decrease.
  • A job that requires heavy lifting or twisting as well as an inactive desk job may contribute to back pain.
  • Back pain is often associated with weak abdominal and back muscles that may not properly support the spine.
  • Exercise can strengthen affected muscles and reduce pain and inflammation. Exercise is not recommended for acute back pain.
  • Once healthy again, exercise frequently to keep your abdominal and back muscles strong, which can help avoid future incidences of back pain.
  • Hot and cold packs can help to relive pain and inflammation. Heat reduces muscle spasms and cold can reduce swelling.

Genes, environment and behaviors all contribute to a person’s lifespan. As researchers continue to study the relationship between health span and lifespan and find ways to delay or prevent disease and disability, one thing is certain. Healthy living is the path to healthy aging. We can all work towards living healthier longer by following some basic principles:

  • Maintain a healthy weight
  • Eat nutritiously
  • Exercise regularly
  • Get sufficient sleep
  • Reduce stress
  • Drink alcohol in moderation
  • Don’t smoke
  • Get sufficient amounts of micronutrients by to discourage illness and encourage wellness

Professional Supplement Center carries these and other high quality supplements for overall health and healthy aging support:

Cal Apatite Bone...Cal Apatite Bone Builder® Forte by Metagenics – This formula provides full spectrum macro and micro minerals that naturally comprise healthy bone. Backed by more than 30 years of research, Cal Apatite Bone Builder Forte® supplies bone health support with vitamin D and premium quality MCHC. Gluten and soy free, Non-GMO formulation.

 

MSM 920MSM 920™ by NuMedica – This high potency formula provides an organic source of sulfur, necessary for collagen production and support of structural and connective tissues, including muscles, tendons and ligaments. Gluten, soy and dairy free, vegetarian formulation.

 

Hyaluronic AcidHyaluronic Acid by Pure Encapsulations – Hyaluronic Acid supports joint comfort and function by promoting healthy synovial fluid, and supporting healthy joint lubrication and shock absorption. Found in all bodily tissues, HA hydrates the skin to provide support for a healthy appearance. Gluten and soy free, Non-GMO formulation.

 

Joint Support...Joint Support Formula by Anabolic Laboratories – This high potency, broad spectrum, 3-part formula is indicated for joint pain, cartilage degeneration, inflammation and decreased mobility. Gluten free formulation.

 

Zyflamend Whole BodyZyflamend Whole Body by New Chapter –  This proprietary herbal blend is formulated to help balance and support the body’s natural healthy inflammation response after exercise. Gluten free, Non-GMO, vegetarian formulation.

 

References:
Number of Americans With Severe Joint Pain Keeps Rising. https://medlineplus.gov/news/fullstory_161349.html
13 Natural Remedies for Arthritis. http://www.health.com/health/gallery/0,,20443624,00.html#exercise-11
Safe Strategies for Using Over-the-Counter Arthritis Drugs. http://www.health.com/health/condition-article/0,,20327304,00.html
How Back Pain Took Over the World. http://www.theatlantic.com/health/archive/2016/10/how-back-pain-took-over-the-world/503243/?utm_source=nl-atlantic-daily-100716
Low Back Pain Fact Sheet. http://www.ninds.nih.gov/disorders/backpain/detail_backpain.htm
Increasing number of Americans suffer from severe joint pain. http://www.cbsnews.com/news/more-americans-suffer-from-severe-joint-pain/