Continuing studies and preliminary clinical trials researching the health benefits of pyrroloquinoline quinone (PQQ), a non-chemical protein found in plant foods, are extremely encouraging. Known as a cofactor or coenzyme, PQQ aids enzymatic reactions that fuel biochemical processes. This natural compound uniquely supports mitochondrial biogenesis or the generation of new mitochondria in aging cells. Mitochondrial dysfunction is recognized as a key biomarker for aging, and is linked to the development of virtually all age related degenerative, chronic and deadly diseases, including type 2 diabetes, heart failure, cardiac dysfunction, and Alzheimer’s and Parkinson’s diseases.
When we age, our mitochondrial energy production diminishes, while the number of mitochondria in our cells significantly lowers. Similar in some ways to CoQ10, which is known to optimize mitochondrial health and energy producing capacity, PQQ is a micronutrient with an antioxidant capacity that provides remarkable defense against mitochondrial decay through its ability to protect mitochondria from oxidative stress. It acts directly on key enzymes involved in cellular energy production and promotes the spontaneous generation of new mitochondria within aging cells. Based on clinical studies, some researchers suggest that PQQ will be the next nutrient superstar with a wide range of benefits for the brain and entire body.
PQQ is not synthesized by the body, yet is believed to be an important nutritional component required for normal growth and development. PQQ is found in miniscule amounts in natto, a fermented soy product, and in foods such as parsley, green peppers and green tea. So, is PQQ the fountain of youth that society has been searching for to optimize health, vitality and longevity? Not quite, however continuing scientific research suggests that PQQ’s high redox recycling ability may give it a pharmacological role in protecting against neurodegeneration and mitochondrial dysfunction. While ongoing investigation on the efficacy of PQQ for conditions that stem from mitochondrial dysfunction proceeds, evidence shows compelling support for PQQ’s role in reducing age-related oxidative stress and rejuvenating healthy mitochondria. Promising research supports PQQ as a potent weapon against cellular aging.
Professional Supplement Center carries these and other high quality products for PQQ supplementation:
Mito-PQQ by Designs for Health – This formula, featuring PQQ combined with adaptogen rhodiola rosea, is designed to support mitochondrial energy production, critical for healthy aging, optimal energy production and free radical defense. Gluten free, Non-GMO vegetarian formulation.
PQQ Plus by Douglas Laboratories – This formula features an optimal daily dose of BioPQQ™ along with clinically backed Alpha GPC in support of optimal neurological health and the maintenance of mitochondrial homeostasis. Gluten free, vegan formula.
MicroPQQ® by Progressive Labs – This scientifically formulated supplement is designed to support mitochondrial biogenesis and optimal energy production.
References:
Rejuvenating Mitochondria with PQQ. http://blog.designsforhealth.com/blog/rejuvenating-mitochondria-with-pqq?
8 Proven Health Benefits of PQQ. https://selfhacked.com/2014/09/11/pqq-review/
The Benefits of PQQ for Aging Support. http://www.globalhealingcenter.com/natural-health/benefits-pqq-aging-support/
PQQ – the next nutrients superstar. http://www.globalhealingcenter.com/natural-health/benefits-pqq-aging-support/
Pyrroloquinoline quinone (PQQ) stimulates mitochondrial biogenesis. http://www.fasebj.org/content/21/6/A1104.2.short
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